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Pickart L, Freedman JH, Loker WJ, Peisach J, Perkins CM, Stenkamp RE, Weinstein B

GSH also acts as the primary intracellular antioxidant, directly neutralizing reactive oxygen species (ROS) and protecting against lipid peroxidation, while serving as a cofactor for enzymes such as glutathione peroxidase (GPx) and glutathione reductase (GR)

Finally, as products of lipid peroxidation appear reactive aldehydes (such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE)) and as well as cyclisation products, including isoprostanes, that have garnered attention as significant signaling molecules 88

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