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This could be attributed to the fact that the assessment of PLGA-based nanoparticles for PD treatment focused mainly on dopamine levels and short-term symptomatic improvements 117,121,124,126

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Observations reviewed encompassed somatosensory neuron protection, peripheral nerve regeneration, attenuation of traumatic brain injury-associated pathological progression, and functional recovery in spinal cord compression models exhibiting axonal necrosis, demyelination, and cyst formation

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