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10.1104/pp.106.077982 9 CannonM

How much do they actually help

Patients need comprehensive information on available treatments, including medications (GnRH agonists, IUDs, NSAIDs), minimally invasive procedures (focused ultrasound, uterine artery embolization), and surgical options like myomectomy or hysterectomy

Despite the high immunosuppressive efficacy, its adverse effects, narrow therapeutic window and high intra- and interpatient variability (IPV) in pharmacokinetics require therapeutic drug monitoring (TDM), which makes treatment with Tac a major challenge for physicians

[DOI] [PMC free article] [PubMed] [Google Scholar] Zhao X, Xue X, Wang C, Wang J, Peng C, Li Y