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Cancer treatments significantly elevate OS through multiple mechanisms: chemotherapeutic agents, particularly alkylating agents and platinum compounds, generate excessive ROS directly damaging sperm DNA and membranes (87, 88), while radiation therapy induces both acute and chronic OS states in testicular tissue, leading to prolonged spermatogenic dysfunction (95)
These changes include higher levels of Enterococcus and Streptococcus species and increased Enterobacteriaceae , while beneficial Bifidobacteria and anti-inflammatory Firmicutes are decreased [21,22,23, 27]
Botox is commonly used to treat the frequent occurrence of migraines, excessive sweating under the arms, uncontrolled drooling, and muscular disorders such as muscle stiffness and spasms
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