Naringenin, an abundant flavanone in citrus fruits (Kaulaskar et al., 2012) and genistein, a natural phytoestrogen from soybean (Valsecchi et al., 2008), have been exhibited analgesic, antioxidant and immunoregulatory properties in sciatic nerve injury models
EMBO Rep 18:569585 Angel LO, Mena S, Estrela JM (2011) Glutathione in cancer cell death
In 2023, the FDA designated BPC-157 as a Category 2 bulk drug substance, meaning it cannot be compounded by commercial pharmaceutical companies, and there is insufficient evidence regarding potential harm to humans
PMID: 18425419
Medications Used for the Treatment of Infectious Diarrhea Drug FDA category Recommendations for pregnancy Recommendations for breastfeeding Albendazole C No human data: probably compatible Ampicillin Azithromycin Ciprofloxacin (all quinolones) Doxycycline Fidaxomicin Furazolidone B B C D B C Metronidazole B Rifaximin C Tetracycline Tinidazole D C Trimethoprim-sulfamethoxazole Vancomycin C C Embryotoxic in animals Avoid in first trimester Human data support improved pregnancy outcomes with helminth eradication Safe Low risk Potential toxicity to cartilage: avoid Contraindicated: teratogenic Low risk but expensive Low risk Limited data Low risk: question of increased risk of cleft lip with or without cleft palate Animal teratogen No human data Not safe: teratogenicity Low risk Limited data Teratogenic Low risk Compatible Limited human data: probably compatible Limited human data: probably compatible Compatible No human data: potential toxicity No human data: potential toxicity Limited human data: potential toxicity No human data: probably compatible Compatible Unsafe Compatible Limited human data: probably compatible Abbreviation: FDA, US Food and Drug Administration
