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The exclusion criteria involve conditions or lifestyle behaviors that result in abnormalities of liver function tests, which can be independently responsible for depleted glutathione levels or inflammation

In support of this idea, it has been reported that 5 mg/kg of resveratrol supplementation increases lipid peroxidation of the heart, liver, and kidney of rats [9]

It is important to maintain a regular dosage and allow sufficient time for the active compounds to exert their full therapeutic effects

Acyl-coenzyme A synthetase long-chain family (ACSL) 4 and lysophosphatidylcholine acyltransferase 3 are critical for ferroptosis because they promote the activation and incorporation of PUFAs into membrane lipids

Abstract Ferroptosis is a type of cell death that depends on iron and reactive oxygen species (ROS)