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Puerarin protects retinal cells against apoptosis by antioxidant mechanisms such as lowering iNOS expression, increasing superoxide dismutase (SOD) activity, and preventing the production of advanced glycation end products (AGEs)

These pathways not only meet the energetic demands of immune activation and inflammation but also shape long-term gene expression through epigenetic mechanisms

This dark reddish-brown, wedge-shaped organ serves the body with everything from digestion to detoxification

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With a high prevalence in developed countries and a significant increase in incidence in developing countries, it has grown to become a global burden 1