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Jager-Wittenaar H, Dijkstra PU, Vissink A, Langendijk JA, van der Laan BFAM, Pruim J, Roodenburg JLN

That's why most research protocols build in a break between cycles, often called a washout period, to let the body reset before starting again

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Gut microbe-generated metabolite trimethylamine-N-oxide as cardiovascular risk biomarker: a systematic review and dose-response meta-analysis