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The US-FDA initially approved the drug in 1942.[7] However, the compound became widely available for routine use in the treatment of B12 deficiency in the early 1950s.[8] Mechanisms of Action Cyanocobalamin is a vital compound for cell division and growth, hematopoiesis, and nucleoprotein and myelin synthesis

Individuals in the highest and mid-tertiles of vitamin B 12 levels had significantly reduced odds of TT deficiency relative to those in the lowest tertile

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