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Could it be that B12 was feeding budding tumors or something

Drug-Disease Interaction: Use Vitcofol Injection with medical advice if you have malabsorption syndrome (difficulty absorbing nutrition from food), bleeding disorders, diabetes, gout, liver/kidney diseases, stomach ulcers, and allergic reactions to medicines

[59] [60] Injection side effects include skin rash, itching, chills, fever, hot flushes, nausea and dizziness

(February 1968)

It is difficult to give a one-size-fits-all answer to the question, "How long does it take for B12 injections to work." It is possible for some individuals to notice the improvement in their symptoms right away, whereas, for others, it may take additional injections to achieve optimal health