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In contrast to Ru(II)-OH or NP2, the nanoparticle formulation NP4 has a carbon fluorinated moiety in the polymeric backbone, which could be used for the transport of O 2 and therefore explain this phenomenon

[123] The metabolism of NAD + remained an area of intense research into the 21st century, with interest heightened after the discovery of the NAD + -dependent protein deacetylases called sirtuins in 2000, by Shin-ichiro Imai and coworkers in the laboratory of Leonard P

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