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10.1002/0471142735.im1412s109 56 TangY.ShiY.GaoY.XuX.HanT.LiJ.et al (2019)

Animal research may appear promising, but animal outcomes do not automatically translate to humans

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[158] Previously, FDA guidelines state that isotretinoin is a contraindication for LASIK refractive surgery, and new findings suggest those guidelines should be reconsidered

Although rare, adverse effects of high-dose vitamin B12 have been reported, including allergic reactions such as fever, rash, itching, hot flushes, dizziness, and nausea, across all cobalamin forms and administration routes (Caballero et al., 2007)