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Positive anti-CCP (94 U) : Anti-cyclic citrullinated peptide (anti-CCP) antibodies are highly specific for rheumatoid arthritis (RA), and their presence strongly supports the diagnosis (Baker, 2026)
Upon activation, Nrf2 translocates to the nucleus, where it binds to antioxidant response elements (AREs) in the DNA, upregulating the production of cellular antioxidant enzymes and other cytoprotective proteins [33]
DAMPs serve as alarm signals within the innate immune system, alerting cells to any damage or to the presence of non-native microbes, which in turn activates host immune responses 68
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