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Componentes destacados

The overall biosynthetic pathway of isoprostanes involves the formation of arachidonyl radicals and peroxyl radical isomers with endocyclization, forming bi-cycloendoperoxide regiomers reduced to F2-isoprostanes (F2-IsoPs)

Studies on nucleotide excision repair-defective cells have shown that unrepaired UV-induced DNA damage can trigger the degradation of Bcl-2, the activation of caspase 3, and the destruction of mitochondrial membrane potential

Retrospective studies also suggested that metformin decreased the risk of TB incidence [119, 120], cavitary TB [118], and mortality associated with diabetes mellitus during TB treatment [121]

doi: 10.1007/978-3-319-64298-7_1 45