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While nightshades have gotten a bad reputation in recent years (Gisele Bndchen famously said she avoided them) because of possible issues with food sensitivities or allergies, the Cleveland Clinic explains that the heart of the issue is their alkaloid content, which is typically only harmful in large doses

Hoefele J, Sudbrak R, Reinhardt R, et al

Even some meat eaters dont absorb it very well (4, Unlike other vitamins, the absorption of vitamin B12 depends on a protein produced in your stomach, called intrinsic factor

Wet skin dilutes the product and reduces absorption

"FDA approves first treatment to increase pain-free light exposure in patients with a rare disorder" (Press release)