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(4) The fatty acid peroxyl radical is then reduced by an electron from the ferrous iron (Fe 2+ ) and protonated, resulting in the formation of FAHP and the iron is re-oxidized to its ferric form (Fe 3+ )

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In summary, the roGFP2 oxidation kinetics of PfGrx fusion constructs reflect at up to micromolar GSSG concentrations the glutathionylation kinetics of the glutaredoxin moiety in accordance with previous intracellular structure-function analyses and data interpretations 15,34,35