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Overall, the evidence supports the view that anabolicandrogenic steroid misuse represents a complex endocrinemetabolic and public-health issue rather than an isolated doping-related practice

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Metabolic syndrome The collective term used to describe the combination of type 2 diabetes mellitus, high blood pressure, dyslipidemia and obesity

349 Aging-related nuclear NAD + decline inhibits the mitochondrially encoded genes via the SIRT1-HIF-1-c-Myc pathway, while boosting NAD + levels rescues the mitochondrial function in old mice in a SIRT1-dependent manner