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Intermittent claudication in peripheral arterial disease In peripheral arterial disease, atherosclerosis of the arteries that supply the lower extremities may diminish blood flow to the point that the metabolic needs of exercising muscles are not sufficiently met, thereby leading to ischemic leg or hip pain known as claudication (see the page on Intermittent Claudication in Peripheral Arterial Disease) (63)

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Glutathione levels decline in many types of tissue as we age, and this decline can have a significant impact on brain health

IGF-1 promotes longitudinal bone growth by insulin-like actions augmenting chondrocyte hypertrophy