*Correspondence: Goran imi, [email protected] Bari, [email protected] This article was submitted to Neuropharmacology, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
The BioCycle study, a study of 259 healthy women, showed that oxidative stress was associated with the severity of PMS symptoms, such as food cravings and crying spells
387, 167178.10.1002/(SICI)1096-9861(19971020)387:2 3.0.CO;2-Z 66 HyderF.FulbrightR
This therapeutic effect was mechanistically linked to reductions in pro-inflammatory cytokines (TNF-, IL-1), enhancement of antioxidant defenses (e.g., increased superoxide dismutase activity), suppression of apoptosis via caspase-3 inhibition, and modulation of NF-B pathwayscollectively yielding neuroprotection and symptomatic relief ( Curcumin shows therapeutic potential for managing peripheral neuropathic pain through multiple mechanisms (Zhang et al., 2020b)
For frequent travelers, this convenience factor alone can justify choosing sublingual over injectable delivery for appropriate peptides
