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Powe DG, Akhtar G, Habashy HO, Abdel-Fatah T, Rakha EA, Green AR, Ellis IO

Targeting inflammasome activation, inhibiting caspase-1, employing anti-inflammatory agents, and modulating the gut microbiota and bile acid metabolism represent promising avenues for developing novel treatments for this common and potentially life-threatening condition

Inflammatory Bowel Disease: Therapy a prednisone dosage of 40 or 60 mg daily is more effective than 20 mg daily, and more adverse effects occur with 60 mg daily

Studies suggest 25-40% of weight lost may come from muscle rather than fat

If discomfort occurs at the injection site, a cold compress or gentle massage may help