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The position of GSH in the model is supported by data showing that mutation of two of the arginines, R73 and R74, results in complete loss of substrate saturation with GSH (with CDNB as the electrophilic second substrate)

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The physical barrier comprises intestinal epithelial cells (IECs), goblet cells (synthesis and release of mucins), Paneth cells (synthetic AMPs), and intestinal stem cells

The only difference between cryptogenic and symptomatic syndromes is that in cryptogenic syndromes the presumed cause cannot be identified (Shellhaas et al

BAC Water is available in 3mL and 10mL vial sizes