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doi: 10.1007/s00011-020-01401-6 23 IbrahimH.PerlA.SmithD.LewisT.KonZ.GoldenbergR.et al

10.1094/MPMI-4-014 42 EdwardsR.DixonD

It is essential for various bodily functions, including: Neutralizing free radicals and lipid peroxides Supporting immune function Detoxifying harmful substances Regenerating other antioxidants such as vitamin C and E Glutathione disulfide (GSSG) plays a crucial role in cellular oxidative stress and detoxification by maintaining the balance between reduced glutathione (GSH) and GSSG, which is vital for cellular health

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The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy