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Subsequently, Yagoda and Yangs groups demonstrated that iron chelators could inhibit this type of cell death, discovered that Ras-selective lethal 3 (RSL3) mimicked Erastins effects in RAS-mutant cells, and found that elevated levels of ROS and iron were closely associated with RAS signaling (Yagoda et al., 2007

Key enzymes involved in the GABA shunt pathway, namely GAD, SSADH, and GABA-T play crucial roles in these processes

doi: 10.1016/j.plaphy.2020.11.035 47 WangJ.ZhangY.YanX.GuoJ

The risks encountered by astronauts exposed to cosmic radiation are outlined in Figure 2 and are discussed below ( Figure 2 2.2.1

Immunologic abnormalities in chronic fatigue syndrome