Researchers must observe the following precautions at all times
The current product is supplied as a 10 mg lyophilised laboratory reference material
severe or persistent upper abdominal pain should prompt urgent medical assessment [10] [11] Dehydration and acute kidney injury (AKI): gastrointestinal fluid losses can lead to dehydration, which may precipitate AKI, particularly in those with pre-existing renal impairment or those taking nephrotoxic medicines Delayed gastric emptying: this may affect the absorption of orally administered medicines, including contraceptive pills and thyroid replacement therapy [11] Injection site reactions: redness, bruising, or discomfort at the subcutaneous injection site Heart rate changes: increases in resting heart rate have been noted with GLP-1 class agents [14] [15] Hypoglycaemia: particularly if used alongside insulin or sulphonylureas Potential pancreatitis risk: a class concern with GLP-1 receptor agonists
To maintain optimal stability, keep the pen away from light, and do not expose it to repeated temperature changes
For subcutaneous injection (most common), pinch the skin into a fold, insert the needle at a 45-degree angle, and inject slowly over 510 seconds
