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At the genomic level, Epitalon modulated the expression of key circadian rhythm genes: Clock expression in leukocytes decreased 1.8-fold, Cry2 expression doubled, and Csnk1e expression in lymphocytes decreased by 2.1-fold, all with statistical significance

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Recent review literature describes BPC-157 as having anti-inflammatory and cytoprotective features across preclinical models, with proposed links to nitric oxide, antioxidant enzyme expression and repair-associated pathway control

& Hoffer, L