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Bcl-2-deficient mice exhibit a reduced number of oocytes and primordial follicles (Hsu et al., 1996

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Consequently, the Trx and Grx systems maintain the balance of thiol-disulfide interactions in the reduction/oxidation conversion of protein forms, which act as target signaling pathways to regulate disulfide stress and may act as crucial triggers to suppress disulfidptosis

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