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In a Regulatory Affairs Report from 2018, Coppens states: After the adoption of the Food Supplements Directive 2002/46, the Commission published a report in 2008 on further harmonization in this area (Commission of the European Communities, 2008)

Further research with these compounds will likely reveal more applications and deepen our understanding of cellular metabolism

To be honest a rather underwhelming result, far from the 20 pounds in 4 weeks they had in the pilot study

[DOI] [PMC free article] [PubMed] [Google Scholar] Balendiran GK, Dabur R, Fraser D

Most non-hormonal treatments only treat hot flushes and night sweats