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10.1038/jes.2015.9 60 WilkeB

The treatment may last until the patient reaches the goal weight

Give yourself 36-48 hours of flexibility after each injection during peak weeks

Intern Med (2013) 52(3):32532

Since previous studies have linked the activation of NRF2 with the repression of lipogenic gene expression 64 , we reasoned that GSH depletion causes oxidation and consequent inactivation of KEAP1 (a repressor of NRF2), thus leading to increased antioxidant and decreased lipogenic gene expression