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Acne occurs as a result of inflammation in the hair follicles in the skin, caused mainly by bacteria of the species propionibacterium acnes

Hydroxocobalamin is a long-acting, highly bioavailable form of B12, making it a preferred choice for both clinical use and B12 deficiency correction

Subcutaneous injections are administered into fat under the skin, so instead of the needle going in at a 90-degree angle, the subcutaneous injection angle is at 45 degrees so that it pierces the skin but not the muscle tissue

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Its compact size resists enzymatic degradation, making it suitable for long-duration laboratory studies of fat metabolism