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Cytosponge-trefoil factor 3 versus usual care to identify Barretts oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial

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Description 5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that consumes NAD+ precursors and is reported to be elevated in aged adipose tissue, obese skeletal muscle, and certain tumor types