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Its found in high concentrations in platelets and in injured tissue thats actively trying to repair

A recent analysis of the USFDA Adverse Event Reporting System revealed that patients taking both metformin and a PPI experienced significantly higher rates of hospitalizations and life-threatening complications related to B12 deficiency (such as severe neuropathy and cognitive decline) compared to those on monotherapy

That said, patterns have emerged that provide starting points for research applications

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