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Copper peptides dont address this immune attack, so they are not a primary treatment

Therefore, overcoming tamoxifen-induced activation of the ARE could increase the efficacy of tamoxifen in treating breast cancer

The countries/territories with the highest number of publications and potential biomarkers evaluated were Brazil, with 23 studies and 78 biomarkers

The process begins with genetic susceptibility, primarily caused by high-risk HLA class II alleles (e.g., HLA-DQ2/DQ8), and is complemented by class I alleles and key non-HLA variants in immunoregulatory genes