No participants developed antibodies against AOD-9604, and no treatment-related serious adverse events led to study withdrawal
B12 injections offer a range of benefits beyond addressing vitamin B12 deficiency, including reducing the risk of associated complications, aiding in weight loss, and addressing hair loss concerns
However, because it influences metabolic pathways, its essential to approach its use cautiously
Fewer B12 molecules means less absorption, resulting in a paler, more subtle pink that some people barely notice
Hong S, Moreno-Navarrete JM, Wei X, Kikukawa Y, Tzameli I, Prasad D, Lee Y, Asara JM, Fernandez-Real JM, Maratos-Flier E, Pissios P. Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization. Nat Med. 2015 Aug;21(8):887-94. doi: 10.1038/nm.3882. Epub 2015 Jul 13. PMID: 26168293; PMCID: PMC4529375