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Under homeostatic conditions, NRF2 is sequestered in the cytoplasm through its interaction with the repressor protein KEAP1
Ookhtens M, Hobdy K, Corvasce MC, Aw TY, Kaplowitz M: Sinusoidal efflux of glutathione in the perfused rat liver
N-terminal ataxin-3 causes neurological symptoms with inclusions, endoplasmic reticulum stress and ribosomal dislocation
By coupling nanoparticles with specific antibodies or ligands, or by leveraging the unique microenvironment of tumor tissue, nanomedicines can accurately target lesions while minimizing damage to normal tissues
The results obtained in the aforementioned study prompted scientists to stipulate that the administration of vitamin C may also modulate the effects of neuroinflammation and ROS activity in the course of migraine [54]
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