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Most of the clonal expansion drivers are depleted targets in the screen, reflecting the role of the gene product in promoting cell fitness, as is the case for Kras (Fig

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Ive had patients come in with B12 levels of 201 pg/ml with the word normal scribbled across it by the doctor

For example, various antibiotics (i.e., macrolide), calcium antagonists, protease-/kinase inhibitors [antivirals for HIV (e.g., booster), SARS-Cov2 (e.g., nirmatrelvir/ritonavir), or CMV (e.g., maribavir)], or antimycotics such as azoles can inhibit the activity of CYP3A enzymes (91, 92)