In some embodiments, the otic formulation or composition comprises about 6% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof
Genetics will account for baseline sperm quality, DNA repair capacity, and receptor sensitivity for peptide signaling
For musculoskeletal or systemic targets, injections are the better-supported route based on existing animal data
The significance of chromium, selenium, and zinc supplementation is another topic of debate
It arises from a combination of endocrine, inflammatory, neural, and intracellular mechanisms (Tong et al., 2022) and is linked to lifestyle factors, including diet (Bruckner et al., 2024)