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doi:10.4103/ijem.ijem_45_24

Aberrant DNA methylation patterns have been identified in patients with HT, leading to gene silencing and altered expression of genes regulating the immune response, along with hypermethylation of specific CpG sites

The TRAVERSE triala large, well-regarded study on TRTdidnt find a significant benefit in preventing worsening insulin resistance in men with prediabetes

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