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However, we showed that the increase of NO resulted in positive regulation of p53, which potentiated the antioxidant defense response mediated by NFE2L2 through direct upregulation of Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1a) [44,45]

High-performance Liquid Chromatography Analysis A LaChrom ELITE system (Hitachi High-Tech Corporation, Tokyo, Japan) was used for the high-performance liquid chromatography (HPLC) analysis, with a L2100 pump, L2200 autosampler, L2300 column oven, and L2455 detector

doi: 10.1371/JOURNAL.PPAT.1001311 158 CornellCTKiossesWBHarkinsSWhittonJL