While significant breakthroughs have been achieved in multimodal modulation of mitochondrial biogenesis, mitophagy, and dynamics, persisting challenges include incomplete elucidation of molecular regulatory networks and genetic foundations, limitations of single-pathway intervention strategies in achieving multi-target coordination, and technical barriers imposed by the selective permeability of the blood-brain barrier (BBB) that hinder clinical translation of mitochondrial-targeted therapies (Meng et al., 2024)
Based on the data acquired from the blank samples, the ASV table was further modified by a sample decontamination step that was carried out with the package decontam (Davis et al., 2018) and 0.0088% of sequences were identified as potential contaminations and eliminated (i.e., DNA extraction blanks and experimental controls)
Alzheimers Dement 9, 1020
Its molecular formula is expressed as C62H98N16O22 with a precise molecular weight of 1419.54 Da 2
Molecular mechanisms involved in the protective effect of the chloroform extract of Selaginella lepidophylla (Hook
