doi: 10.1073/pnas.2119824119 [DOI] [PMC free article] [PubMed] [Google Scholar] 11.Kazmirczak F, Hartweck LM, Vogel NT, Mendelson JB, Park AK, Raveendran RM, et al
425,426 In a murine model of AD, the administration of GLP-1RAs effectively reduced the levels of pathological markers associated with AD
Segawa, K
I absolutely have to do exercise just like I have to brush my teeth. Rhonda Patrick She works out about 5 to 6 hours a week total broken down like this: Two sessions a week that are CrossFit style, one hour each, first 30 minutes is heavy strength training, last 30 minutes is HIIT (rowing machine, assault bike, lighter cleans with more reps) Two more sessions a week with her girlfriends, about an hour and 20 each, same style but more social and more recovery time between sets Running about 4 to 6 miles a week total, sometimes with her husband, which she genuinely enjoys Weekend hikes with the family, sometimes with a sprint up a hill, but mostly just moving in nature Even just 10 minutes of vigorous exercise immediately increases neuronal connections in the brain The data for this is insane 9 minutes a day of vigorous bursts (3 minutes, 3 times) links to a 40% reduction in all-cause mortality, 40% reduction in cancer mortality, and 50% reduction in cardiovascular mortality The biggest unexpected benefit of heavy strength training was not physical I would say the biggest effect was on my brain and the ability to handle stress better
Experimental observations suggest that it participates in coordinated cellular repair processes by influencing fibroblast activity, modulating angiogenic signaling, and regulating the expression of structural extracellular matrix components such as collagen and elastin
