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For those really suffering, we can add medications like ondansetron (Zofran) to stop nausea in its tracks or ketorolac (Toradol) to ease those awful body aches all delivered directly to where they're needed most

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As a result, increased stiffness triggers the translocation of the transcription factor co-activators Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) to the nucleus where they interact with the transcriptional enhanced associate domain (TEAD) family of transcription factors to induce gene expression [85]

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[PubMed] [Google Scholar] 201.Ferrucci L, Balducci L