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Clinical trials involving approximately 900 participants showed that AOD-9604 had no effect on IGF-1 levels and no negative effects on carbohydrate metabolism

Priority research needs include large-scale randomized controlled trials to establish efficacy and safety, dose-ranging studies to optimize treatment protocols, long-term safety studies particularly regarding cancer risk, and comparative effectiveness research with established therapies

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The large NAD+ base acts as the foundation, while the 10mg each of MOTS-c and 5-Amino-1MQ make this primarily a concentrated MOTS-c / 5-Amino-1MQ pairing