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Cleavage of Boc groups with 4 M HCl/dioxane followed by a coupling reaction with the -carboxyl group of the N -hydroxysuccinimide active ester of Boc-Glu--OtBu resulted in the corresponding glutathione disulfide-1,1- 13 C with fully protected N and C-terminals

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pH 7.4) and 50% of (20% ACN, 0.1% FA) at final concentrations of 20 nM to 1 M and 0.5 M to 10 M for GS-CAM-TPP, 50 nM to 1 M and 0.5 M to 10 M for GSS-CAM-TPP supplemented with 25 M of deuterated internal standards GS-CAM- d 15 TPP and 5 M of deuterated internal standards GSS-CAM- d 15 TPP

Advances in the pharmacological study of Chinese herbal medicine to alleviate diabetic nephropathy by improving mitochondrial oxidative stress