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5.2 Is It Safe for Everyone
Karim, A
Furthermore, a different approach using intragastrically administered rotenone (5 mg/Kg) in mice showed that the accumulation and aggregation of -synuclein in neurons of the dorsal motor nucleus of the vagus (DMV) and the intermediolateral nucleus (IML) in the spinal cord was accompanied by the selective loss of dopaminergic neurons and astrogliosis, suggesting that the gastric administration of rotenone through the connection of the enteric nervous system (ENS) with anatomical structures of the CNS also induces PD-like features [11,19]
The vitamin retention highly depends on the type of food, the method used, temperature, and process duration 102,106,130,134,162,180,295,296,363,365,375,376,377,378,379,380,381,382,383,384,385,386,387,388,389,390
The mass spectrometer coupled to UPLC was a XEVO-TQS (Waters Corporation, Milford, MA, USA) used with the following conditions: polarity API+, corona needle discharge electric current (uA): 0.54
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