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The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases

Fenn K, Strandwitz P, Stewart EJ, Dimise E, Rubin S, Gurubacharya S, et al

[6] Caution is advised in patients with advanced renal impairment or those receiving dialysis, given the renal clearance of carnitine and the risk of accumulation

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Progress in these areas will require not only rigorous experimental design but also close interdisciplinary collaboration between pharmacologists, formulation scientists, veterinary clinicians, and regulatory stakeholders to ensure translational relevance, safety, and real-world applicability