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Oxidative stress has also been reported as a major factor in the formation of uterine fibroid 48, 49 , indicating that these findings concur with previous investigations 50, 51

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proposed that motor cortex sensitivity (MCS) scoring via MRI could serve as an auxiliary diagnostic tool for differentiating ALS-like syndromes, especially when UMN dysfunction is ambiguous (342)

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3 Oxidative stress Oxidative stress is a disbalance caused by excessive production of prooxidant substances such as ROS and RNS and/or the antioxidant systems working inefficiently ( in vivo primarily by the mitochondrial respiratory chain during aerobic metabolism ( via a reaction between nitric oxide (NO) and superoxide, and nitrosoperoxycarbonate, generated via a reaction between peroxynitrite and carbon dioxide

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