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In addition, ZnT4 mRNA was found to be overexpressed in tumor samples acquired through radical prostatectomy versus normal tissues

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In preclinical studies, HG has been shown to improve outcomes in conditions such as sepsis, acute lung injury, hepatic injury, pancreatitis, cardiac arrest, traumatic injury, acute kidney injury, and brain injury

Consistent with the finding that there is no apparent increase in enzymatic activity, the transcript levels of genes encoding -glutamylcysteine synthetases did not change significantly either

To our surprise, the c-circle results revealed that both cancer cell lines dramatically increased ALT activity to a level higher than what was seen in the untreated controls (Fig