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This particular subject was further elucidated in subsequent sections

R-ALA (R-form): This is the biologically active version that your body produces naturally

Macromolecules 53, 91589186

Due to the high demand of glutamine, this amino acid is also used for imaging based on 18F-labeled glutamine tracers in preclinical and clinical studies, especially when the use of 18F-FDG is not feasible, like in the brain [15,16]

Interestingly, this P R RA R insertion generates a furin cleavage site on S-protein at the S1/S2 multi-basic region, considered as a potential gain of function for the viral pathogen