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Omega-3 polyunsaturated fatty acids improve the antioxidative defense in rat astrocytes via an Nrf2-dependent mechanism

Selection of DCM/ethanol system for the nanoprecipitation method was based on an evaluation of the suspendablity of DDA-GSH-AuNCs after phase transfer in various solvents that include good and poor solvents for PLGA as detailed in Fig

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Inadequate dietary folate supply and/or gene polymorphisms of the remethylation enzymes may compromise the function of methionine/homocysteine circle with subsequent elevation of plasma homocysteine levels, and reduced methyl group generation for transmethylation reaction that may be associated with adverse clinical consequences [17,18,19]

GSH is present and synthesized in the cytosol of all mammalian cells by a two-step regulated process (see Figure 1) [42]