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doi: 10.1096/fj.202001807 56 De PasqualeV.QuiccioneM

[PubMed: 19605939] 15

Upon entering the body through diet, Se is mainly taken by the liver (Burk and Hill, 2015) to be distributed to the extrahepatic tissue

Under typical dietary conditions, carbohydrate metabolism supplies the majority of energy requirements

Additionally, fraxetin mitigates inflammation by reducing pro-inflammatory cytokine release and enhances mitochondrial function, addressing key pathological factors of fibrosis